Community Water Fluoridation Serves as an example of a perfect public health intervention. Because the benefits can be readily provided to everyone served by a fluoridated public water system, large groups of people can be protected in a manner that does not discriminate against any group, regardless of race, socioeconomic status, gender, or any other demographic categorization. People are protected continuously in a way that requires no conscious effort on their part to participate.
Community water fluoridation has been widely practiced since 1945 in this country and it is the 20th-century adaptation of a naturally occurring process. It does not involve adding anything to the water that is not already there. Virtually all sources of drinking water in the United States contain some fluoride.1 Fluoridation is the adjustment of the amount of the essential trace element fluoride in water to provide for the proper protection of teeth and bones. It is a form of nutritional supplementation that is not unlike the addition of vitamins to milk, breads, and fruit drinks; iodine to table salt; and both vitamins and minerals to breakfast cereals, grains, and pasta.
Michael W. Easley, DDS, MPH, is Associate Professor, Department of Oral Biology, and Director of the National Center for Fluoridation Policy and Research at the School of Dental Medicine, State University of New York at Buffalo. E-mail: email@example.com
Status of Community Water Fluoridation
Ten states, the District of Columbia, and Puerto Rico currently mandate fluoridation for designated communities through legislation. Other state legislatures (Washington and Hawaii) are currently considering mandatory fluoridation bills. In addition, several other states and many cities have required fluoridation by administrative regulation.
The total US population receiving the benefits of fluoridated water now stands officially at 145 million, or 62.2% of those on community water systems.2 Over 14300 water systems serving more than 10 500 American communities provide this public health benefit to their citizens. 2 Official reports substantially underestimate the number of persons receiving the benefits of fluoridation. Many communities, including Los Angeles and Las Vegas, have implemented fluoridation since 1992, when the last National Fluoridation Census was published.
Health Benefits of Community Water fluoridation
The dental benefits resulting from continued exposure of children and adults to optimal levels of water-borne fluoride have been documented for more than three-quarters of a century in thousands of studies on fluorides and fluoridation. More than 3700 studies have been done on fluorides since 1970 alone.3 The prevailing scientific literature from reputable peer-reviewed journals provides adequate documentation of the effectiveness, efficiency, economy, and safety of community water fluoridation for both children and adults. Community water fluoridation has been validated as a primary public health intervention.
Techniques Employed by The Unprincipled Opposition
Bernhardt and Sprague compiled a list of techniques frequently used by the opposition in attempting to stop the process of fluoridation.4 Several additional techniques have been categorized and listed in this paper.
Once fluoridation legislation has been introduced, fluorophobic extremists attempt to convince state and local elected officials to remain neutral, rather than make the appropriate health policy decision to fluoridate the water supply. Opponents often attempt to give the impression that there is “scientific” legitimacy for their positions by quoting “alternative” medicine Web sites or using naturopaths, chiropractors, “holistic” dentists, “environmental” physicians, or “health food” promoters as chief spokespersons in hearings, correspondence, and distributed propaganda.
Antifluoridationists try to convince the elected officials to refer the issue to public vote rather than to decide the issue through the legislative process. Fluorophobics attempt this because they are much more adept at running a scare campaign focused on the public than they are at convincing skeptical legislators to agree with their views. In those rare instances where fluoridation has been subjected to referendum, only a small percentage of the elections have been lost in recent years.5 Moreover, they are lost not because of issues of science, but because of low voter turnout and because of ruthless scare campaigns directed at the most emotionally vulnerable citizens.
The unprincipled opposition institutes massive letter-writing and phone-calling campaigns designed to fool the legislators into thinking that “everyone is against fluoridation,” when in fact the vast majority of citizens desire, accept, and approve of fluoridation.5·7 The fluorophobics also bombard the print media with many letters to the editor in an attempt to enlist unsuspecting citizens in their cause.
The antifluoridationists burden legislators with reams of propaganda falsely claiming “evidence of harm,” or inappropriately claiming that fluoridation interferes with their “freedom of choice,” even though legitimate research results universally refute claims of harm and the courts have repeatedly held that fluoridation interferes with no one’s constitutional freedoms. Actually, there are several functional freedoms with which fluoridation interferes: the freedoms to endure infection, pain, poor nutrition, lost work days, missed school days, higher taxes, higher health-care premiums, and uncomfortable dentures.
Legislators will sometimes let themselves be neutralized because they overestimate the extent of the opposition, incorrectly concluding that it might be better to let the electorate make the decision.
By arousing serious doubts about safety, antifluoride extremists give local elected officials an easy excuse to delay favorable action. Thus, not only has the legislative official been neutralized, but also the antifluoridationists have gained more time to bombard the public with propaganda designed to tum public opinion against fluoridation.
The Big Lie
Fluorophobics repeatedly allege that fluoride causes things like cancer, kidney disease, heart disease, genetic damage, osteoporosis, Down syndrome, AIDS, Alzheimer’s disease, nymphomania, and practically every other malady known to a man-a veritable laundry list of unproven allegations.
These laundry lists are repeated so often in antifluoride pamphlets, letters to the editor and phone calls to talk-radio shows that the public may actually begin to believe the unsubstantiated claims. In order to lend some aura of legitimacy to the unproved claims, naturopaths and other purveyors of “alternative medicine” modalities frequently appear as the authors of such letters.
The appearance of an allegation in print (such as in the letters to the editor section of local newspapers) is often believed by the public to be evidence of the allegation’s validity. The public incorrectly assumes that the “authorities” (in this case print media editors) would not allow allegations to be printed if they were untrue. Thus, the media often become unwitting pawns of the antifluoridationists, unless the newspapers are large enough and sophisticated enough to have employed qualified and responsible science editors to eliminate from publication those letters that are scientifically unsound and that constitute a potential for harm to the public.
In this technique, an out-of-context statement is used to imply a cause-and-effect relationship between fluoridation and some evil outcome. For example, fluorophobics claim that “fluoride is poison, so don’t let them put it in our water.” This statement ignores the principle that toxicity is related to the dose of a substance and not to mere exposure to the substance. Chlorine, vitamin D, table salt, iodine, antibiotics, and even water serve as excellent examples of substances that are harmful in the wrong amounts but beneficial in the correct amounts.
Another example of this is: “Fluoride causes dental fluorosis or mottling.” By itself, this claim fails to take into account the source of the fluoride, the amount of fluoride, the mechanism of fluoride exposure, or the time of exposure as related to the dental age of the person exposed. Community water fluoridation is not responsible for causing dental fluorosis. Limited numbers of the population have a mild to moderate form of fluorosis that has been primarily attributed to improper supplementation of fluoride through careless prescriptive practices and the inappropriate ingestion of large amounts of fluoride-containing dentifrice by young children not properly supervised during tooth brushing.
Moreover, the extremely mild form of fluorosis occasionally related to fluoridation is no more a pathological condition than is having blond hair or blue eyes. Furthermore, adults cannot acquire dental fluorosis. Antifluoridationists frequently adopt the intellectually dishonest practice of showing photographs of teeth with tetracycline staining or of extremely rare cases of severe dental fluorosis that have occurred in other countries due to extensive industrial pollution or long-term ingestion of extremely high naturally occurring fluoride levels from noncommunal water sources. They then falsely claim that this will be the result for anyone, adults included, who drinks fluoridated water.
“The majority of AIDS victims come from fluoridated cities.” Believe it or not, this half-truth was frequently made in the mid-1980s by the most notorious of the antifluoride health alarmists in his misguided attempts to scare San Francisco’s public into stopping fluoridation in that city. He continued to make this claim even after the discovery of the virus that causes AIDS.
While most AIDS patients coincidentally reside in major metropolitan areas and most major metropolitan areas are fluoridated (45 of the 50 largest cities in the United States),” the antifluoridationists’ logic never did explain the high incidence of AIDS in Los Angeles, San Diego, or Newark, New Jersey, all non-fluoridated. This same health alarmist apparently changed his mind and claimed during his unsuccessful 1992 campaign for the US presidency that AIDS is caused by the AIDS drug AZT, implying a plot by medical professionals, drug companies, and the government to infect certain groups with AIDS.9
A frequently used fluorophobic tome is that “while one glass of fluoridated water will not kill anyone, it is the glass after glass of fluoridated water, as with cigarette after cigarette, that takes its toll in human health and life.”10 This technique uses a guilt-by-association ploy, attempting to link the known health risks of cigarette smoking (for which there is substantial scientific evidence) to alleged risks from drinking fluoridated water (of which there is no scientific evidence).
Another oft-used claim by fluorophobics is that “insufficient research has been carried out to prove absolute safety, and therefore consumers and government officials are urged to wait until all doubt about safety of fluoridation has been ‘scientifically’ resolved.” This ludicrous argument could be used indefinitely in that it is impossible to ever prove absolute safety for all time for anything. Unqualified acceptance of this argument would mean that literally all technological advancements achieved in the age of science would have to be eliminated. Thousands of studies and untold risk-benefit analyses have shown that fluoridation is safe and effective for the entire population.
Quoting of Inaccurate Statements and the Use of Statements Taken Out of Context
The best way to illustrate this common fluorophobic technique is to refer to two frequently used antifluoridation publications, The Lifesavers [sic} Guide to Fluorida~ tion10 (a pamphlet) and Fluoride: the Aging Factor11 (a monograph). Both use essentially the same “scientific references,” both are distributed frequently in campaigns opposing fluoridation, and both documents were marketed by their author as “scientific documents.” The one-sheet pamphlet claims over 250 references.
A group of 20 scientists and public health officials from around the United States decided to actually track down the original references in order to evaluate their validity as used by the author. It took two years and the production of a 184-page monograph to adequately document that this pamphlet was a piece of scientific nonsense. The refutation was appropriately entitled Abuse of the Scientific Literature in an Antifluoridation Pamphlet.12 What the group found through its Herculean effort was astonishing:
- Of the 250 references, only 48% were from reputable scientific journals. Some were actually references to letters to the editors of newspapers.
- Two hundred forty of the 250 citations were incompletely referenced.
- Twenty-one of the references were incorrectly cited. Please note that use of incomplete and/or incorrect citations is a common ploy used by authors who do not want their readers to be able to verify the validity of their claims or their references.
- Amazingly, 116 of the 250 references had no relevance to community water fluoridation whatsoever.
- Many of the references actually supported fluoridation with the works of respected scientists selectively quoted and misrepresented in order to make them appear to discourage the use of fluorides.
- Finally, many of the statements of “hazard” were taken from obscure or hard-to-locate foreign journals. After two years of effort, the researchers were unsuccessful in confirming that some of the cited articles or journals even existed.
Quoting of Experts
Many of the “experts” to whom antifluoride statements are attributed are self-proclaimed experts. For example, John Yiamouyiannis frequently introduces himself as the “world’s leading expert on fluorides and the biological effects of fluoridation.” Only he and a handful of fluorophobics accept his self-proclaimed world leadership in fluoride research.
Some of the quoted experts have legitimate academic or professional credentials, although not necessarily in disciplines qualified to serve as experts in health research specific to fluorides.
Antifluoridationists occasionally find a credentialed individual to speak against mainstream science. The statements by these marginalized individuals, while of questionable authority, are often exploited by the fluorophobics. Unfortunately, a most flagrant abuse of the public trust occasionally occurs when physicians or dentists, for whatever personal reasons, use their professional standing in the community to argue against fluoridation. Such behavior clearly violates professional ethics, the principles of science, and community standards of practice.
Some nationally known figures who may have opposed fluoridation early in their professional lives (prior to the accumulation of overwhelming scientific evidence in its favor) often have their earlier statements quoted by fluorophobics despite having changed their position to one of support for fluoridation. For example, the fluorophobics repeatedly claim that Nobel Laureate and physician Hugo Theorell “condemns” fluoridation when, in fact, he publicly changed his position to one of support as far back as 1967.
The public is further misled when antifluoride zealots utilize the services of “alternative medicine” spokespersons to “prove” that the medical community is divided in its position on fluoridation. Unable to discriminate between legitimate scientists and purveyors of unproven therapies, some in the public see the dispute as a conflict between competing health-care philosophies and ideologies.
Because alleged conspiracies are difficult to disprove, they are a favorite of the health alarmists. The alleged “conspirators” often include the American Medical Association, the American Dental Association, the American Council on Science and Health, the equipment and chemical supply companies, the Communist Party, both the aluminum and phosphate fertilizer industries, toothpaste manufacturers, and any other organization appearing to be threatening to the antifluoridationists. Highest on their list of conspirators is “the government,” including the Public Health Service, the Environmental Protection Agency, the prestigious National Institutes of Health, the world-renowned Centers for Disease Control, and the Food and Drug Administration.
Antifluoridationists frequently play on the current phobias and concerns of the public by describing fluoridation in ecologically linked or environmentally loaded terms or phrases such as, “pollutant,” “toxic waste product,” “chemical by-product,” “dumped in the water,” or “forced down our throats.”
Fluoride is frequently linked by fluorophobics with words like “poison,” “genetic damage,” “cancer,” “AIDS,” or “artificial.” Such words conjure up fear when linked to something to which people think they will be unwittingly exposed.
The Debate Ploy
The opponents of fluoridation often try to entice unsuspecting media commentators, government officials, or program planners into holding a debate on the “pros and cons” of fluoridation, even though there are no “cons” to fluoridation. A favorite tactic of the fluorophobics is to argue for a debate so that “the people can decide who is right.”
Proponents of fluoride are then often trapped into consenting to public debates. Jarvis has published an excellent list of a number of reasons for not debating health quacks, a list that is also applicable to that class of health quacks known as antifluoridationists. 13 Jarvis’s 5-item list follows:
(1) The purpose of the debate is to win the audience, not to discover truth. Science is not decided by de-bating in a public forum, but by careful experimentation, confirmation of findings through in-dependently conducted experiments, submission of all findings to qualified colleagues and peers for critical analysis, and publication of findings in reputable peer-reviewed journals. In a debate, even though the proponents are likely to win the debate, they are just as likely to lose the audience.
(2) In media circles, there is a saying that “everyone is the same size on TV.” In other words, debates give the illusion that a scientific controversy exists when no credible people support the fluorophobics’ view. Public debates also promote the illusion that there are equal numbers of “scientists” on each side of the issue. The vision of “dueling PhDs” or “dueling doctors” encourages the public to reject fluoridation until the “experts on both sides can agree.”
(3) An opponent of fluoridation, utilizing the laundry list approach, can present more misinformation in five minutes than can be refuted in five hours, thus fostering confusion on the part of the public. Proponents are never provided enough time to adequately refute the fluorophobics’ charges, because complete refutations, by their nature, take much longer than the sound-bite-length antifluoridation charges. As previously discussed, an extensive two-year effort was required to develop a 184-page textbook to refute allegations made in a one-sheet antifluoridation pamphlet.
(4) Public exposure favors the opponents, enabling them to gain name recognition for the materials, services, or viewpoints they are promoting. Like parasites, opponents steal undeserved credibility just by sharing the stage with respected scientists who are there to defend fluoridation.
(5) It is impossible to compete against opponents without appearing to discredit them personally. When a proponent is arguing against a health alarmist who is spreading misinformation, the proponent cannot separate the antiscience message from the antiscience messenger. Moreover, the debate format often results in the public’s sympathy vote for the obvious underdog, the fluerophobics. Since fluorophobics are quick to threaten to file lawsuits even when they have no case, their detractors are exposed to legal harassment by the opponents’ attorneys. One can be assured, though, that while threats to sue honest scientists are frequently made, few suits have actually been filed, and none have been successfully pursued by antifluoridationists.
Five additional techniques of health alarmists not listed by Bernhardt and Sprague include the use of contrived organizations, subversion of the media, commandeering established organizations, misuse of electronic publishing, and commandeering meetings.
Use of Contrived Organizations
After repeatedly being embarrassed for not being able to identify legitimate scientific studies that confirmed any of their many allegations and after having their own poorly researched propaganda pieces continually rejected by peer-reviewed journals because the articles were unable to meet rigorous scientific standards, opponents often form their own pseudoscientific organizations. Organizations with names like the International Society for Fluoride Research, the International Academy of Oral Medicine and Toxicology, the Preventive Dental Health Association, the National Health Action Committee, and the Safe Water Foundation sound impressive to the uninformed. They are, in reality, front organizations for the anti-fluoridationists with few members. Moreover, most of the members are untrained, uncredentialed nonprofessionals who lack scientific qualifications. Antifluoridationists frequently try to pass off propaganda pieces as “research” in Fluoride, the journal of the International Society for Fluoride Research. While authors of articles appearing in Fluoride claim that the journal is peer-reviewed, it is not. The journal does not meet any of the standard requirements of a scientific journal nor is it indexed in Index Medicus.
Subversion of the Media
Throughout some antifluoridation campaigns, fluorophobics have been able to recruit the media to support their views for the following reasons:
- Media are more interested in publicizing a controversy (such as a debate) than in accurately representing an issue.
- It is more profitable for the media to do a sensational story on the “dangers” of fluoridation than one on the many scientifically sound but emotionally unexciting reasons for supporting fluoridation.
- The antiestablishment and antiscience view of fluorophobics is almost always more flamboyant and interesting to a media bent on finding examples of David versus Goliath or John Q. Public fighting City Hall.
- Scientific rebuttals to flamboyant anrifluoridation claims are often, by their nature, dry, unemotional, complex, difficult to explain in lay terms, hard for the public to grasp conceptually, and difficult for the media to interpret and report.
Commandeering Established Organizations
There have been several instances in which anti-fluoridationists have commandeered established organizations in an attempt to hijack the organizations’ credibility for the antifluoride cause. Two recent examples involve the Pennsylvania Sierra Club and one of the collective bargaining units for the US Environmental Protection Agency.
- In August 1997, a renegade member of the Pennsylvania chapter of the Sierra Club held a press conference in Harrisburg in which she claimed that the Sierra Club called for a ban to fluoridation in that state.14 Within a few days the officers of the chapter issued an official statement rebuking the renegade member’s action and declaring that the press conference was held “without the knowledge or authorization of any Pennsylvania Sierra Club officer.”15
- The US Environmental Protection Agency (EPA) has over 18 000 employees represented mostly by 4 collective bargaining units. The smallest of these bargaining units was Local 2050 of the National Federation of Federal Employees (NFFE), a union that variously claimed to represent about 900, 1000, 1100, and finally 1550 EPA employees, but whose dues-paying membership was apparently much less. About 20 dissident members of the union held a meeting on July 2, 1997, at which a minority voted to oppose California’s mandatory fluoridation law.16-17 A subsequent press conference falsely claimed that all union members unanimously approved the resolution. Subsequent mass mailings of propaganda leaflets from two of the union’s antifluoride activists falsely implied that the USEPA opposed fluoridation. l6-l7
Moreover, within a few months of the issuance of the “press release,” Local 2050 of the NFFE ceased operations, with its membership being absorbed by Local 280 of the National Treasury Employees’ Union (NTEU).17 While Local 280 of the NTEU has never published an official position on fluoridation, several former officers of NFFE Local 2050 imply that the NTEU supports the NFFE action. The activists have printed articles and letters for anti fluoride Web sites under the NTEU banner.
Misuse of Electronic Publishing
Numerous antifluoridation Web sites have been established in order to promote the antifluoride political agenda and to recruit converts to the movement. In addition, many “alternative” medicine Web sites have included antifluoridation sections as part of their marketing efforts, along with information that opposes traditional scientific medical practice; attacks immunization programs; promotes herbalism and other dubious therapies; and solicits patients for naturopaths, chiropractors, environmental physicians, holistic dentists, and other purveyors of unproven remedies and practices.
Some examples of antifluoridanon Web sites are listed in Table 1. Many of these contain “articles,” letters, endorsements, or references to purveyors of “alternative” or “complementary” medicine. Some also contain links to Web sites operated by practitioners and marketers of nonscientific therapies.
Unable to establish professional credibility with civic organizations or the media, antifluoridation spokespersons must often attempt to hijack scheduled meetings or hearings in order to gain a forum from which to market their propaganda. It is not uncommon for anti-fluoridationists to attempt to utilize question-and-answer periods in public meetings to lecture the audience on the “pitfalls” of fluoridation rather than to ask questions of scheduled speakers. Town meetings, allegedly scheduled to provide opportunities for proponents and opponents to present their cases, often serve as a convenient forum in which antifluoridation spokespersons try to dominate the available time. Print and broadcast media, often as a result of incessant baiting by the opponents, will attempt to lure proponents into a debate-type interview opposite fluorophobes.
Antifluoridation activism provides opportunities for “alternative” medicine zealots and purveyors of unproven health modalities to publicize their “philosophical” differences with science-based health care. But fluoridation remains a safe, effective, efficient, economical, environmentally sound, and socially equitable public health measure to prevent dental disease. It also fulfills all the requirements of an excellent public policy. Despite some minor opposition that sporadically delayed fluoridation’s implementation in some locales, substantial progress has been made toward achieving the long-term goal of universal fluoridation in the United States.
Table 1 Popular Antifluoride Websites
Leading Edge Antifluoridation Web site www.trufax.org/menu/chem.html
Fluoride Issues www.sonic.net/~ kryptox/fluoride.htm
International Center for Nutritional Research www.icnr.com/AuoridePres.html
Zero Waste America www.zerowasteamerica.com/Fluoride.htm
Stop Fluoridation USA-Information Index www.rvi.net/~fluoride/index.htm
Fluorosis Prevention Program www.ia4u.net/~sherrell/
Preventive Dental Health Association emporium.turnpike.net/p/pdha/health.htm
Calgary (Alberta) Antifluoride Web site www.cadvision.com/fluoride/index.htm
Mountain View (CA) Citizens for Safe Drinking Water www.nofluoride.com/
Holistic Healing Web site www.holisticmed.com/
California Citizens for Health www.citizenshealth.org/
Citizens for Mercury Relief-The Toxicity Newsletter www.talkinternational.com/fluoridel.htm
Fircrest Atlas Orthogonal Chiropractic Clinic www.atlaschiro.com/
1. Hodge HC, Smith FA. Fluorine chemistry. In: Si-mons JH (ed.). Fluorine Chemistry. New York: Academic Press; 1965.
2. Centers for Disease Control. Fluoridation Census, 1992. Atlanta: US Department of Health and Human Services, Public Health Service; 1993.
3. Easley MW. Celebrating 50 years of fluoridation: a public health success story. Br Dent]. 1995;178(2):72-75.
4. Bernhardt M, Sprague B. The poisonmongers. In: Barrett S, Rovin S (eds.). The Tooth Robbers. Philadelphia, PA: G. F. Stickley;l980:l-8.
5. Easley MW. The status of community water fluoridation in the United States. Public Health Rep. 1990;105(4): 348-353.
6. Gallup Organization. Approval of Fluoridating Drinking Water: Survey of Parents. December 1991.
7. Gallup Organization. 1998 Consumers Opinions Regarding Community Water Fluoridation. American Dental Association Survey Center. June 1998.
8. Hinman AR, Sterritt GR, Reeves TG. The US experience with fluoridation. Community Dent Health. 1996;13 (2):5-9.
9. John Yiamouyiannis for President. John Yiamouyiannis Is Running for President: Platform Statement. 1992.
10. Yiamouyiannis J. Lifesavers Guide to Fluoridation. Delaware, OH: Safe Water Foundation; 1983.
11. Yiamouyiannis, J. Fluoride: The Aging Factor. Dela-ware, OH: Health Action Press; 1983.
12. Wulf CA, Hughes KF, Smith K, Easley MW (eds.). Abuse of the Scientific Literature in an Anti-fluoridation Pamphlet. Columbus, OH: American Oral Health Institute Press; 1988. 13. Jarvis W. Should we debate quacks? California Council Against Health Fraud Newsletter. 1983;6:7.
14. Sierra club to take on water fluoridation. Pittsburgh Post-Gazette. August 13, 1997.
15. Coleman, P. Not authorized. Letter to the Editor. Pittsburgh Post-Gazette. August 24, 1997.
16. Citizens for Safe Drinking Water. EPA scientists take stand against fluoridation (press release). July 2, 1997.
17. Hirzy JW. Narrative history of the union. National Treasury Employees Union, Local 280. Available at: www.nteu280.org/history.htm.
From The National Council For Reliable Health Information Americans Ignorant of Interactions Between Herbs and Prescriptions
The Los Angeles Times took a long, hard look at the growing problem of mixing herbs and other dietary supplements with prescription medications. An article by health writer Jane E. Allen starts with a report of a retired engineer who was on a prescription blood thinner discovered that the ginkgo Biloba and garlic pills he was taking also inhibit blood clotting. More and more people are self-medicating with herbs and nutritional supplements. Some $13 .9 billion a year in dietary supplements were sold in 1998, according to Nutrition Business Journal in San Diego. A survey for Prevention magazine found 49% of adults had used herbs in the last year and 24% used them regularly. In November 1998 JAMA reported that 42% of Americans used alternative medicine and 40% didn’t tell their physicians.
Lack of Research. There simply isn’t enough research yet to know just what all the interactions are. But there is evidence for a number of warning areas: St. John’s wort should not be mixed with antidepressants because it intensifies their effects; St. John’s wort should not be mixed with the heart medicine digoxin because it reduces the effectiveness of digoxin; ginkgo Biloba and aspirin should not be combined with prescription blood thinners because of potential excessive bleeding; and, licorice root should not be mixed with the heart drug Lanoxin, because such could deplete the body’s store of potassium.
Information Sources. Some Web sites have information about these interactions. A spokesperson for Nature Made supplements, a product of Pharmavite Corp, puts information on interactions on its Web site. The company also offers a toll-free phone line for questions and sends materials to pharmacists. Some individual pharmacists have become knowledgeable about nutritional supplements. Also, the NIH has funded botanical research centers at the University of Illinois and UCLA so information on supplements can be made available to physicians across the country. Much more research needs to be done so that information on drug-herb interactions can be available to the public.